Empagliflozin Attenuates Non-Alcoholic Fatty Liver Disease (NAFLD) in High Fat Diet Fed ApoE((-/-)) Mice by Activating Autophagy and Reducing ER Stress and Apoptosis

Aims/hypothesis: SGLT-2 inhibitors (SGLT-2i) have been studied as potential treatments against NAFLD, showing varying beneficial effects. The molecular mechanisms mediating these effects have not been fully clarified. Herein, we investigated the impact of empagliflozin on NAFLD, focusing particularl...

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Detalles Bibliográficos
Autores principales: Nasiri-Ansari, Narjes, Nikolopoulou, Chrysa, Papoutsi, Katerina, Kyrou, Ioannis, Mantzoros, Christos S., Kyriakopoulos, Georgios, Chatzigeorgiou, Antonios, Kalotychou, Vassiliki, Randeva, Manpal S., Chatha, Kamaljit, Kontzoglou, Konstantinos, Kaltsas, Gregory, Papavassiliou, Athanasios G., Randeva, Harpal S., Kassi, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829901/
https://www.ncbi.nlm.nih.gov/pubmed/33467546
http://dx.doi.org/10.3390/ijms22020818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829901/
https://www.ncbi.nlm.nih.gov/pubmed/33467546
http://dx.doi.org/10.3390/ijms22020818

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