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Phenanthrene impacts zebrafish cardiomyocyte excitability by inhibiting I(Kr) and shortening action potential duration

Air pollution is an environmental hazard that is associated with cardiovascular dysfunction. Phenanthrene is a three-ringed polyaromatic hydrocarbon that is a significant component of air pollution and crude oil and has been shown to cause cardiac dysfunction in marine fishes. We investigated the ca...

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Detalles Bibliográficos
Autores principales: Kompella, Shiva N., Brette, Fabien, Hancox, Jules C., Shiels, Holly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829948/
https://www.ncbi.nlm.nih.gov/pubmed/33475719
http://dx.doi.org/10.1085/jgp.202012733