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DNA Methylation Levels in Mononuclear Leukocytes from the Mother and Her Child Are Associated with IgE Sensitization to Allergens in Early Life

DNA methylation changes may predispose becoming IgE-sensitized to allergens. We analyzed whether DNA methylation in peripheral blood mononuclear cells (PBMC) is associated with IgE sensitization at 5 years of age (5Y). DNA methylation was measured in 288 PBMC samples from 74 mother/child pairs from...

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Detalles Bibliográficos
Autores principales: Acevedo, Nathalie, Scala, Giovanni, Merid, Simon Kebede, Frumento, Paolo, Bruhn, Sören, Andersson, Anna, Ogris, Christoph, Bottai, Matteo, Pershagen, Göran, Koppelman, Gerard H., Melén, Erik, Sonnhammer, Erik, Alm, Johan, Söderhäll, Cilla, Kere, Juha, Greco, Dario, Scheynius, Annika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830007/
https://www.ncbi.nlm.nih.gov/pubmed/33466918
http://dx.doi.org/10.3390/ijms22020801