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Targeting the Proline–Glutamine–Asparagine–Arginine Metabolic Axis in Amino Acid Starvation Cancer Therapy

Proline, glutamine, asparagine, and arginine are conditionally non-essential amino acids that can be produced in our body. However, they are essential for the growth of highly proliferative cells such as cancers. Many cancers express reduced levels of these amino acids and thus require import from t...

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Detalles Bibliográficos
Autores principales: Kuo, Macus Tien, Chen, Helen H. W., Feun, Lynn G., Savaraj, Niramol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830038/
https://www.ncbi.nlm.nih.gov/pubmed/33477430
http://dx.doi.org/10.3390/ph14010072