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Alteration of Neural Stem Cell Functions in Ataxia and Male Sterility Mice: A Possible Role of β-Tubulin Glutamylation in Neurodegeneration

Ataxia and Male Sterility (AMS) is a mutant mouse strain that contains a missense mutation in the coding region of Nna1, a gene that encodes a deglutamylase. AMS mice exhibit early cerebellar Purkinje cell degeneration and an ataxic phenotype in an autosomal recessive manner. To understand the under...

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Detalles Bibliográficos
Autores principales: Sheikh, Abdullah Md., Yano, Shozo, Tabassum, Shatera, Omura, Koji, Araki, Asuka, Mitaki, Shingo, Ito, Yoshie, Huang, Shuai, Nagai, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830091/
https://www.ncbi.nlm.nih.gov/pubmed/33466875
http://dx.doi.org/10.3390/cells10010155