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Does KRAS Play a Role in the Regulation of Colon Cancer Cells-Derived Exosomes?

Exosomes are cell-derived nanovesicles, and lately, cancer-derived exosomes have been reported to carry KRAS protein, which contributes to the malignancy of many cancers. In this study, farnesylthiosalicylic acid (FTS) was used to inhibit the activities of mutated KRAS in colon cancer SW480 cells to...

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Detalles Bibliográficos
Autores principales: Eng, Shu-Kee, Imtiaz, Ilma Ruzni, Goh, Bey-Hing, Ming, Long Chiau, Lim, Ya-Chee, Lee, Wai-Leng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830101/
https://www.ncbi.nlm.nih.gov/pubmed/33466836
http://dx.doi.org/10.3390/biology10010058