Solution NMR Structure of the SH3 Domain of Human Caskin1 Validates the Lack of a Typical Peptide Binding Groove and Supports a Role in Lipid Mediator Binding

SH3 domains constitute an important class of protein modules involved in a variety of cellular functions. They participate in protein-protein interactions via their canonical ligand binding interfaces composed of several evolutionarily conserved aromatic residues forming binding grooves for typical...

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Detalles Bibliográficos
Autores principales: Tőke, Orsolya, Koprivanacz, Kitti, Radnai, László, Merő, Balázs, Juhász, Tünde, Liliom, Károly, Buday, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830187/
https://www.ncbi.nlm.nih.gov/pubmed/33467043
http://dx.doi.org/10.3390/cells10010173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830187/
https://www.ncbi.nlm.nih.gov/pubmed/33467043
http://dx.doi.org/10.3390/cells10010173

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