Gene Methylation and Silencing of WIF1 Is a Frequent Genetic Abnormality in Mantle Cell Lymphoma

We have previously shown that the Wnt canonical pathway (WCP) is constitutively active in most cases of mantle cell lymphoma (MCL). Here, we aimed to elucidate the mechanisms underlying this biochemical deregulation. We hypothesized that gene methylation/silencing of WIF1 (Wnt inhibitory factor-1),...

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Detalles Bibliográficos
Autores principales: Alshareef, Abdulraheem, Peters, Anthea C., Gélébart, Pascal, Chen, Will, Lai, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830226/
https://www.ncbi.nlm.nih.gov/pubmed/33477402
http://dx.doi.org/10.3390/ijms22020893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830226/
https://www.ncbi.nlm.nih.gov/pubmed/33477402
http://dx.doi.org/10.3390/ijms22020893

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