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In silico assessment and sonochemical synthesis of 2-alkynyl 3-chloropyrazines as prospective ligands for SARS-CoV-2

The recent global pandemic caused by COVID-19 has triggered an intense effort worldwide towards the development of an effective cure for this disease. In our effort we have explored the 2-alkynyl substituted 3-chloropyrazine framework as a potential template for the design of molecules for this purp...

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Detalles Bibliográficos
Autores principales: Satyanarayana, M.V., Reddy, Alugubelli Gopi, Yedukondalu, M., Tej, Mandava Bhuvan, Hossain, Kazi Amirul, Rao, Mandava Venkata Basaveswara, Pal, Manojit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830244/
https://www.ncbi.nlm.nih.gov/pubmed/33518802
http://dx.doi.org/10.1016/j.molstruc.2021.129981