The Bile Salt Export Pump: Molecular Structure, Study Models and Small-Molecule Drugs for the Treatment of Inherited BSEP Deficiencies

The bile salt export pump (BSEP/ABCB11) is responsible for the transport of bile salts from hepatocytes into bile canaliculi. Malfunction of this transporter results in progressive familial intrahepatic cholestasis type 2 (PFIC2), benign recurrent intrahepatic cholestasis type 2 (BRIC2) and intrahep...

Descripción completa

Detalles Bibliográficos
Autores principales: Sohail, Muhammad Imran, Dönmez-Cakil, Yaprak, Szöllősi, Dániel, Stockner, Thomas, Chiba, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830293/
https://www.ncbi.nlm.nih.gov/pubmed/33466755
http://dx.doi.org/10.3390/ijms22020784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830293/
https://www.ncbi.nlm.nih.gov/pubmed/33466755
http://dx.doi.org/10.3390/ijms22020784

Ejemplares similares