Directed Evolution of the Methanosarcina barkeri Pyrrolysyl tRNA/aminoacyl tRNA Synthetase Pair for Rapid Evaluation of Sense Codon Reassignment Potential

Genetic code expansion has largely focused on the reassignment of amber stop codons to insert single copies of non-canonical amino acids (ncAAs) into proteins. Increasing effort has been directed at employing the set of aminoacyl tRNA synthetase (aaRS) variants previously evolved for amber suppressi...

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Detalles Bibliográficos
Autores principales: Schwark, David G., Schmitt, Margaret A., Fisk, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830368/
https://www.ncbi.nlm.nih.gov/pubmed/33477414
http://dx.doi.org/10.3390/ijms22020895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830368/
https://www.ncbi.nlm.nih.gov/pubmed/33477414
http://dx.doi.org/10.3390/ijms22020895

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