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Transcriptional Regulation of PIK3CD and PIKFYVE in T-Cell Acute Lymphoblastic Leukemia by IKAROS and Protein Kinase CK2

IKAROS, encoded by the IKZF1 gene, is a DNA-binding protein that functions as a tumor suppressor in T cell acute lymphoblastic leukemia (T-ALL). Recent studies have identified IKAROS’s novel function in the epigenetic regulation of gene expression in T-ALL and uncovered many genes that are likely to...

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Detalles Bibliográficos
Autores principales: Dovat, Elanora, Song, Chunhua, Hu, Tommy, Rahman, Mohammad Atiqur, Dhanyamraju, Pavan Kumar, Klink, Morgann, Bogush, Daniel, Soliman, Mario, Kane, Shriya, McGrath, Mary, Ding, Yali, Desai, Dhimant, Sharma, Arati, Gowda, Chandrika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830534/
https://www.ncbi.nlm.nih.gov/pubmed/33467550
http://dx.doi.org/10.3390/ijms22020819