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Genetic Screening for Potential New Targets in Chronic Myeloid Leukemia Based on Drosophila Transgenic for Human BCR-ABL1

SIMPLE SUMMARY: Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by the presence of the Philadelphia chromosome that encodes for the tyrosine kinase protein BCR-ABL1 from the Breakpoint Cluster Region (BCR) sequence and the Abelson (ABL1) gene. Despite BCR-ABL1 being one...

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Detalles Bibliográficos
Autores principales: Lo Iacono, Marco, Signorino, Elisabetta, Petiti, Jessica, Pradotto, Monica, Calabrese, Chiara, Panuzzo, Cristina, Caciolli, Francesca, Pergolizzi, Barbara, De Gobbi, Marco, Rege-Cambrin, Giovanna, Fava, Carmen, Giachino, Claudia, Bracco, Enrico, Saglio, Giuseppe, Frassoni, Francesco, Cilloni, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830713/
https://www.ncbi.nlm.nih.gov/pubmed/33466839
http://dx.doi.org/10.3390/cancers13020293