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Lithium Reduces Migration and Collagen Synthesis Activity in Human Cardiac Fibroblasts by Inhibiting Store-Operated Ca(2+) Entry

Cardiac fibrosis plays a vital role in the pathogenesis of heart failure. Fibroblast activity is enhanced by increases in store-operated Ca(2+) entry (SOCE) and calcium release-activated calcium channel protein 1 (Orai1) levels. Lithium regulates SOCE; however, whether therapeutic concentrations of...

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Detalles Bibliográficos
Autores principales:	Chen, Pao-Huan, Chung, Cheng-Chih, Lin, Yuan-Feng, Kao, Yu-Hsun, Chen, Yi-Jen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830715/ https://www.ncbi.nlm.nih.gov/pubmed/33467715 http://dx.doi.org/10.3390/ijms22020842

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