Cargando…

Optimized 5-Fluorouridine Prodrug for Co-Loading with Doxorubicin in Clinically Relevant Liposomes

Liposome-based drug delivery systems have allowed for better drug tolerability and longer circulation times but are often optimized for a single agent due to the inherent difficulty of co-encapsulating two drugs with differing chemical profiles. Here, we design and test a prodrug based on a ribosyla...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Debra, Vogus, Douglas, Krishnan, Vinu, Broto, Marta, Pusuluri, Anusha, Zhao, Zongmin, Kapate, Neha, Mitragotri, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830726/
https://www.ncbi.nlm.nih.gov/pubmed/33467652
http://dx.doi.org/10.3390/pharmaceutics13010107