Targeting S100B with Peptides Encoding Intrinsic Aggregation-Prone Sequence Segments

S100 proteins assume a diversity of oligomeric states including large order self-assemblies, with an impact on protein structure and function. Previous work has uncovered that S100 proteins, including S100B, are prone to undergo β-aggregation under destabilizing conditions. This propensity is encode...

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Detalles Bibliográficos
Autores principales: Cristóvão, Joana S., Romão, Mariana A., Gallardo, Rodrigo, Schymkowitz, Joost, Rousseau, Frederic, Gomes, Cláudio M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830867/
https://www.ncbi.nlm.nih.gov/pubmed/33467751
http://dx.doi.org/10.3390/molecules26020440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830867/
https://www.ncbi.nlm.nih.gov/pubmed/33467751
http://dx.doi.org/10.3390/molecules26020440

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