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Modulating Protein–Protein Interactions by Cyclic and Macrocyclic Peptides. Prominent Strategies and Examples

Cyclic and macrocyclic peptides constitute advanced molecules for modulating protein–protein interactions (PPIs). Although still peptide derivatives, they are metabolically more stable than linear counterparts, and should have a lower degree of flexibility, with more defined secondary structure conf...

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Detalles Bibliográficos
Autores principales: González-Muñiz, Rosario, Bonache, María Ángeles, Pérez de Vega, María Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830901/
https://www.ncbi.nlm.nih.gov/pubmed/33467010
http://dx.doi.org/10.3390/molecules26020445