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Sensitive Detection of KRAS Mutations by Clustered Regularly Interspaced Short Palindromic Repeats
Kirsten rat sarcoma viral oncogene (KRAS) is the isoform most frequently mutated in human tumors. Testing for activating KRAS mutations has important implications for diagnosis and the personalized medicine of cancers. The current techniques for detecting KRAS mutations have moderate sensitivity. Th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830957/ https://www.ncbi.nlm.nih.gov/pubmed/33467412 http://dx.doi.org/10.3390/diagnostics11010125 |