Double Mutant Cycles as a Tool to Address Folding, Binding, and Allostery

Quantitative measurement of intramolecular and intermolecular interactions in protein structure is an elusive task, not easy to address experimentally. The phenomenon denoted ‘energetic coupling’ describes short- and long-range interactions between two residues in a protein system. A powerful method...

Descripción completa

Detalles Bibliográficos
Autores principales: Pagano, Livia, Toto, Angelo, Malagrinò, Francesca, Visconti, Lorenzo, Jemth, Per, Gianni, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830974/
https://www.ncbi.nlm.nih.gov/pubmed/33467625
http://dx.doi.org/10.3390/ijms22020828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830974/
https://www.ncbi.nlm.nih.gov/pubmed/33467625
http://dx.doi.org/10.3390/ijms22020828

Ejemplares similares