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Supra-Molecular Assemblies of ORAI1 at Rest Precede Local Accumulation into Puncta after Activation

The Ca(2+) selective channel ORAI1 and endoplasmic reticulum (ER)-resident STIM proteins form the core of the channel complex mediating store operated Ca(2+) entry (SOCE). Using liquid phase electron microscopy (LPEM), the distribution of ORAI1 proteins was examined at rest and after SOCE-activation...

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Detalles Bibliográficos
Autores principales: Peckys, Diana B., Gaa, Daniel, Alansary, Dalia, Niemeyer, Barbara A., de Jonge, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831003/
https://www.ncbi.nlm.nih.gov/pubmed/33466866
http://dx.doi.org/10.3390/ijms22020799