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Supra-Molecular Assemblies of ORAI1 at Rest Precede Local Accumulation into Puncta after Activation
The Ca(2+) selective channel ORAI1 and endoplasmic reticulum (ER)-resident STIM proteins form the core of the channel complex mediating store operated Ca(2+) entry (SOCE). Using liquid phase electron microscopy (LPEM), the distribution of ORAI1 proteins was examined at rest and after SOCE-activation...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831003/ https://www.ncbi.nlm.nih.gov/pubmed/33466866 http://dx.doi.org/10.3390/ijms22020799 |