Cargando…
Supra-Molecular Assemblies of ORAI1 at Rest Precede Local Accumulation into Puncta after Activation
The Ca(2+) selective channel ORAI1 and endoplasmic reticulum (ER)-resident STIM proteins form the core of the channel complex mediating store operated Ca(2+) entry (SOCE). Using liquid phase electron microscopy (LPEM), the distribution of ORAI1 proteins was examined at rest and after SOCE-activation...
Autores principales: | Peckys, Diana B., Gaa, Daniel, Alansary, Dalia, Niemeyer, Barbara A., de Jonge, Niels |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831003/ https://www.ncbi.nlm.nih.gov/pubmed/33466866 http://dx.doi.org/10.3390/ijms22020799 |
Ejemplares similares
-
Thiol dependent intramolecular locking of Orai1 channels
por: Alansary, Dalia, et al.
Publicado: (2016) -
Cell-wide mapping of Orai1 channel activity reveals functional heterogeneity in STIM1-Orai1 puncta
por: Dynes, Joseph L., et al.
Publicado: (2020) -
Quantification of EGFR-HER2 Heterodimers in HER2-Overexpressing Breast Cancer Cells Using Liquid-Phase Electron Microscopy
por: Peckys, Diana B., et al.
Publicado: (2021) -
STIM1 Phosphorylation at Y361 Recruits Orai1 to STIM1 Puncta and Induces Ca(2+) Entry
por: Yazbeck, Pascal, et al.
Publicado: (2017) -
Canaliculitis in supernumerary puncta and canaliculi
por: Yong, Ku Chui, et al.
Publicado: (2011)