Hot-Melt Extruded Amorphous Solid Dispersion for Solubility, Stability, and Bioavailability Enhancement of Telmisartan

Telmisartan (TEL, an antihypertensive drug) belongs to Class II of the Biopharmaceutical Classification System (BCS) because of its poor aqueous solubility. In this study, we enhanced the solubility, bioavailability, and stability of TEL through the fabrication of TEL-loaded pH-modulated solid dispe...

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Detalles Bibliográficos
Autores principales: Giri, Bhupendra Raj, Kwon, Jaewook, Vo, Anh Q., Bhagurkar, Ajinkya M., Bandari, Suresh, Kim, Dong Wuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831136/
https://www.ncbi.nlm.nih.gov/pubmed/33477557
http://dx.doi.org/10.3390/ph14010073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831136/
https://www.ncbi.nlm.nih.gov/pubmed/33477557
http://dx.doi.org/10.3390/ph14010073

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