Cargando…

Improvement of sensory neuron growth and survival via negatively regulating PTEN by miR-21-5p-contained small extracellular vesicles from skin precursor-derived Schwann cells

BACKGROUND: Patients with peripheral nerve injury (PNI) often suffer from hypoxic ischemic impairments, in particular when combined with vascular damage, causing neuronal dysfunction and death. Increasing attention has been paid on skin precursor-derived Schwann cells (SKP-SCs), and previous study h...

Descripción completa

Detalles Bibliográficos
Autores principales: Cong, Meng, Shen, Mi, Wu, Xia, Li, Yan, Wang, Liting, He, Qianru, Shi, Haiyan, Ding, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831194/
https://www.ncbi.nlm.nih.gov/pubmed/33494833
http://dx.doi.org/10.1186/s13287-020-02125-4