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No observed effect on brain vasculature of Alzheimer’s disease-related mutations in the zebrafish presenilin 1 gene

Previously, we found that brains of adult zebrafish heterozygous for Alzheimer’s disease-related mutations in their presenilin 1 gene (psen1, orthologous to human PSEN1) show greater basal expression levels of hypoxia responsive genes relative to their wild type siblings under normoxia, suggesting h...

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Detalles Bibliográficos
Autores principales: Barthelson, Karissa, Newman, Morgan, Nowell, Cameron J., Lardelli, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831246/
https://www.ncbi.nlm.nih.gov/pubmed/33494778
http://dx.doi.org/10.1186/s13041-021-00734-5