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Development of Three-Dimensional Human Intestinal Organoids as a Physiologically Relevant Model for Characterizing the Viral Replication Kinetics and Antiviral Susceptibility of Enteroviruses

Enteroviruses are important causes of hand, foot, and mouth disease, respiratory infections, and neurological infections in human. A major hurdle for the development of anti-enterovirus agents is the lack of physiologically relevant evaluation platforms that closely correlate with the in vivo state....

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Detalles Bibliográficos
Autores principales: Tsang, Jessica Oi-Ling, Zhou, Jie, Zhao, Xiaoyu, Li, Cun, Zou, Zijiao, Yin, Feifei, Yuan, Shuofeng, Yeung, Man-Lung, Chu, Hin, Chan, Jasper Fuk-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831294/
https://www.ncbi.nlm.nih.gov/pubmed/33477611
http://dx.doi.org/10.3390/biomedicines9010088