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Quantification of Huntington’s Disease Related Markers in the R6/2 Mouse Model

Huntington’s disease (HD) is caused by an expansion of CAG triplets in the huntingtin gene, leading to severe neuropathological changes that result in a devasting and lethal phenotype. Neurodegeneration in HD begins in the striatum and spreads to other brain regions such as cortex and hippocampus, c...

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Detalles Bibliográficos
Autores principales: Etxeberria-Rekalde, Estibaliz, Alzola-Aldamizetxebarria, Saioa, Flunkert, Stefanie, Hable, Isabella, Daurer, Magdalena, Neddens, Joerg, Hutter-Paier, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831778/
https://www.ncbi.nlm.nih.gov/pubmed/33505246
http://dx.doi.org/10.3389/fnmol.2020.617229