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Quantification of Huntington’s Disease Related Markers in the R6/2 Mouse Model
Huntington’s disease (HD) is caused by an expansion of CAG triplets in the huntingtin gene, leading to severe neuropathological changes that result in a devasting and lethal phenotype. Neurodegeneration in HD begins in the striatum and spreads to other brain regions such as cortex and hippocampus, c...
Autores principales: | Etxeberria-Rekalde, Estibaliz, Alzola-Aldamizetxebarria, Saioa, Flunkert, Stefanie, Hable, Isabella, Daurer, Magdalena, Neddens, Joerg, Hutter-Paier, Birgit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831778/ https://www.ncbi.nlm.nih.gov/pubmed/33505246 http://dx.doi.org/10.3389/fnmol.2020.617229 |
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