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Physicochemical Characterization of a Co-Amorphous Atorvastatin-Irbesartan System with a Potential Application in Fixed-Dose Combination Therapy

The aim of this study was to characterize a 1:1 molar ratio of a pharmacologically relevant co-amorphous atorvastatin-irbesartan (ATR-IRB) system obtained by quench cooling of the crystalline ATR/IRB physical mixture for potential use in the fixed-dose combination therapy. The system was characteriz...

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Detalles Bibliográficos
Autores principales: Skotnicki, Marcin, Jadach, Barbara, Skotnicka, Agnieszka, Milanowski, Bartłomiej, Tajber, Lidia, Pyda, Marek, Kujawski, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831949/
https://www.ncbi.nlm.nih.gov/pubmed/33477672
http://dx.doi.org/10.3390/pharmaceutics13010118