Mycobacterium tuberculosis ESX-1-secreted substrate protein EspC promotes mycobacterial survival through endoplasmic reticulum stress-mediated apoptosis

EsxA, secreted by the ESAT-6 secretion system 1 (ESX-1) secretion system, is considered the major Mycobacterium tuberculosis (Mtb) virulence determinant. However, the roles of the individual ESX-1 substrates, such as EspC, remain unclear due to their interdependency for secretion with EsxA. Here, we...

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Detalles Bibliográficos
Autores principales: Guo, Qinglong, Bi, Jing, Wang, Honghai, Zhang, Xuelian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Tuberculosis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832037/
https://www.ncbi.nlm.nih.gov/pubmed/33290182
http://dx.doi.org/10.1080/22221751.2020.1861913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832037/
https://www.ncbi.nlm.nih.gov/pubmed/33290182
http://dx.doi.org/10.1080/22221751.2020.1861913

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