Cargando…

Mycobacterium tuberculosis ESX-1-secreted substrate protein EspC promotes mycobacterial survival through endoplasmic reticulum stress-mediated apoptosis

EsxA, secreted by the ESAT-6 secretion system 1 (ESX-1) secretion system, is considered the major Mycobacterium tuberculosis (Mtb) virulence determinant. However, the roles of the individual ESX-1 substrates, such as EspC, remain unclear due to their interdependency for secretion with EsxA. Here, we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Qinglong, Bi, Jing, Wang, Honghai, Zhang, Xuelian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Tuberculosis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832037/ https://www.ncbi.nlm.nih.gov/pubmed/33290182 http://dx.doi.org/10.1080/22221751.2020.1861913

Ejemplares similares

Gut dysbacteriosis attenuates resistance to Mycobacterium bovis infection by decreasing cyclooxygenase 2 to inhibit endoplasmic reticulum stress
por: Wang, Haoran, et al.
Publicado: (2022)

EspH is a hypervirulence factor for Mycobacterium marinum and essential for the secretion of the ESX-1 substrates EspE and EspF
por: Phan, Trang H., et al.
Publicado: (2018)

Modern Beijing sublineage of Mycobacterium tuberculosis shift macrophage into a hyperinflammatory status
por: Tong, Jingfeng, et al.
Publicado: (2022)

Discrepancy in the transmissibility of multidrug-resistant mycobacterium tuberculosis in urban and rural areas in China
por: Li, Meng, et al.
Publicado: (2023)

Timing of Mycobacterium tuberculosis exposure explains variation in BCG effectiveness: a systematic review and meta-analysis
por: Trauer, James M, et al.
Publicado: (2021)

More than Mycobacterium tuberculosis: site-of-disease microbial communities, and their functional and clinical profiles in tuberculous lymphadenitis
por: Nyawo, Georgina R, et al.
Publicado: (2023)

High clustering rate and genotypic drug-susceptibility screening for the newly recommended anti-tuberculosis drugs among global extensively drug-resistant Mycobacterium tuberculosis isolates
por: Trisakul, Kanwara, et al.
Publicado: (2022)

Revisiting tuberculous pleurisy: pleural fluid characteristics and diagnostic yield of mycobacterial culture in an endemic area
por: Ruan, Sheng-Yuan, et al.
Publicado: (2012)

Accuracy of the InnowaveDX MTB/RIF test for detection of Mycobacterium tuberculosis and rifampicin resistance: a prospective multicentre study
por: Deng, Yunfeng, et al.
Publicado: (2023)

ESX Secretion-Associated Protein C From Mycobacterium tuberculosis Induces Macrophage Activation Through the Toll-Like Receptor-4/Mitogen-Activated Protein Kinase Signaling Pathway
por: Guo, Qinglong, et al.
Publicado: (2019)

BCG-specific IgG-secreting peripheral plasmablasts as a potential biomarker of active tuberculosis in HIV negative and HIV positive patients
por: Ashenafi, Senait, et al.
Publicado: (2013)

H(2)O(2) concentration-dependent kinetics of gene expression: linking the intensity of oxidative stress and mycobacterial physiological adaptation
por: Wu, Mengying, et al.
Publicado: (2022)

The ESX-4 substrates, EsxU and EsxT, modulate Mycobacterium abscessus fitness
por: Lagune, Marion, et al.
Publicado: (2022)

Pictorial essay: Orbital tuberculosis
por: Narula, Mahender K, et al.
Publicado: (2010)

Prevalence and predictors of tuberculosis infection among people living with HIV in a high tuberculosis burden context
por: Njagi, Lilian Nkirote, et al.
Publicado: (2023)

Imaging features of extraaxial musculoskeletal tuberculosis
por: Vanhoenacker, Filip M, et al.
Publicado: (2009)

Mycobacterium paragordonae is an emerging pathogen in human pulmonary disease: clinical features, antimicrobial susceptibility testing and outcomes
por: Li, Yuanchun, et al.
Publicado: (2022)

Genomic epidemiology sheds light on the emergence and spread of Mycobacterium bovis Eu2 Clonal Complex in Portugal
por: Pereira, André C., et al.
Publicado: (2023)

Development, assessment and validation of a novel prediction nomogram model for risk identification of tracheobronchial tuberculosis in patients with pulmonary tuberculosis
por: Qiu, Qian, et al.
Publicado: (2023)

Targeting protein biotinylation enhances tuberculosis chemotherapy
por: Tiwari, Divya, et al.
Publicado: (2018)

Identification of eight-protein biosignature for diagnosis of tuberculosis
por: Yang, Qianting, et al.
Publicado: (2020)

Tuberculosis preventive treatment among individuals with inactive tuberculosis suggested by untreated radiographic abnormalities: a community-based randomized controlled trial
por: Zhang, Haoran, et al.
Publicado: (2023)

Magnetic resonance imaging in central nervous system tuberculosis
por: Trivedi, Richa, et al.
Publicado: (2009)

An evaluation of tuberculosis contact investigations against national standards
por: Cavany, Sean M, et al.
Publicado: (2017)

BTS clinical statement for the diagnosis and management of ocular tuberculosis
por: Kon, Onn Min, et al.
Publicado: (2022)

Designing molecular diagnostics for current tuberculosis drug regimens
por: Georghiou, Sophia B., et al.
Publicado: (2023)

Multidisciplinary tuberculosis care: leveraging the role of hospital pharmacists
por: Iskandar, Deni, et al.
Publicado: (2023)

Incidence of tuberculosis and the influence of surveillance strategy on tuberculosis case-finding and all-cause mortality: a cluster randomised trial in Indian neonates vaccinated with BCG
por: Jenum, Synne, et al.
Publicado: (2018)

Diagnostic benefits of adding EspC, EspF and Rv2348-B to the QuantiFERON Gold In-tube antigen combination
por: Villar-Hernández, R., et al.
Publicado: (2020)

Association of diabetes and tuberculosis: impact on treatment and post-treatment outcomes
por: Jiménez-Corona, María Eugenia, et al.
Publicado: (2013)

Monitoring tuberculosis contact tracing outcomes in Western Sydney, Australia
por: Parvaresh, Laila, et al.
Publicado: (2018)

Association between bacterial homoplastic variants and radiological pathology in tuberculosis
por: Grandjean, Louis, et al.
Publicado: (2020)

Human pathogenic Mycobacterium kansasii (former subtype I) with zoonotic potential isolated from a diseased indoor pet cat, Japan
por: Fukano, Hanako, et al.
Publicado: (2021)

Real-world impact of the fixed-dose combination on improving treatment outcomes of drug-susceptible tuberculosis: a comparative study using multiyear national tuberculosis patient data
por: Ki, Min Seo, et al.
Publicado: (2023)

Primary laryngeal tuberculosis mimicking laryngeal carcinoma: CT scan features
por: El Kettani, N Ech-Cherif, et al.
Publicado: (2010)

Contact investigation of tuberculosis in Brunei Darussalam: Evaluation and risk factor analysis
por: Chaw, Liling, et al.
Publicado: (2022)

Adjunctive Zoledronate + IL-2 administrations enhance anti-tuberculosis Vγ2Vδ2 T-effector populations, and improve treatment outcome of multidrug-resistant tuberculosis(1)
por: Shen, Hongbo, et al.
Publicado: (2022)

High prevalence of latent tuberculosis and bloodborne virus infection in a homeless population
por: Aldridge, Robert W, et al.
Publicado: (2018)

Presentation and healthcare delays among people with tuberculosis in London, and the impact on treatment outcome
por: Evenden, Poppy, et al.
Publicado: (2019)

Biomarkers of iron metabolism facilitate clinical diagnosis in M ycobacterium tuberculosis infection
por: Dai, Youchao, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_pv7nt68cer8ahcu0e9ucieme8t