Characterization of pncA Mutations and Prediction of PZA Resistance in Mycobacterium tuberculosis Clinical Isolates From Chongqing, China

Pyrazinamide (PZA) is widely used to treat drug-sensitive or multidrug resistance tuberculosis. However, conventional PZA susceptibility tests of clinical isolates are rather difficult because of the requirement of acid pH. Since resistance to pyrazinamide is primary mediated by mutation of pncA, an...

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Detalles Bibliográficos
Autores principales: Li, Kun, Yang, Zhongping, Gu, Jing, Luo, Ming, Deng, Jiaoyu, Chen, Yaokai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832174/
https://www.ncbi.nlm.nih.gov/pubmed/33505367
http://dx.doi.org/10.3389/fmicb.2020.594171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832174/
https://www.ncbi.nlm.nih.gov/pubmed/33505367
http://dx.doi.org/10.3389/fmicb.2020.594171

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