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Expanding virus susceptibility spectrum of MDBK cells by expressing host receptors nectin 4 and TfR

Cell-based vaccine manufacturing is a flexible and cost-effective approach for vaccine production which, however, requires cell adaptation to new vaccine strains. Generating one omnipotent or semi-omnipotent cell line feasible for the production of multiple viruses could help resolve this problem. W...

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Detalles Bibliográficos
Autores principales: Han, Peiyu, Zhang, Xuanhao, Yang, Siming, Dai, Xiaofeng, Lv, Qing, Hua, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832251/
https://www.ncbi.nlm.nih.gov/pubmed/33301791
http://dx.doi.org/10.1016/j.jviromet.2020.114038