Enhancing the Physiochemical Properties of Puerarin via L-Proline Co-Crystallization: Synthesis, Characterization, and Dissolution Studies of Two Phases of Pharmaceutical Co-Crystals

Puerarin (PUE) is a Chinese traditional medicine known to enhance glucose uptake into the insulin cells to downregulate the blood glucose levels in the treatment of type II diabetes. Nevertheless, the bioavailability of pristine PUE is limited due to its poor solubility and low intestinal permeabili...

Descripción completa

Detalles Bibliográficos
Autores principales: Inam, Muhammad, Liu, Lu, Wang, Jian-Wei, Yu, Ka-Xi, Phan, Chi-Uyen, Shen, Jie, Zhang, Wen-Hua, Tang, Guping, Hu, Xiurong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832312/
https://www.ncbi.nlm.nih.gov/pubmed/33477727
http://dx.doi.org/10.3390/ijms22020928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832312/
https://www.ncbi.nlm.nih.gov/pubmed/33477727
http://dx.doi.org/10.3390/ijms22020928

Ejemplares similares