ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response

ApoE4, a strong genetic risk factor for Alzheimer disease, has been associated with increased risk for severe COVID-19. However, it is unclear whether ApoE4 alters COVID-19 susceptibility or severity, and the role of direct viral infection in brain cells remains obscure. We tested the neurotropism o...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Cheng, Zhang, Mingzi, Garcia, Gustavo, Tian, E., Cui, Qi, Chen, Xianwei, Sun, Guihua, Wang, Jinhui, Arumugaswami, Vaithilingaraja, Shi, Yanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Short Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832490/
https://www.ncbi.nlm.nih.gov/pubmed/33450186
http://dx.doi.org/10.1016/j.stem.2020.12.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832490/
https://www.ncbi.nlm.nih.gov/pubmed/33450186
http://dx.doi.org/10.1016/j.stem.2020.12.018

Ejemplares similares