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ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response
ApoE4, a strong genetic risk factor for Alzheimer disease, has been associated with increased risk for severe COVID-19. However, it is unclear whether ApoE4 alters COVID-19 susceptibility or severity, and the role of direct viral infection in brain cells remains obscure. We tested the neurotropism o...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832490/ https://www.ncbi.nlm.nih.gov/pubmed/33450186 http://dx.doi.org/10.1016/j.stem.2020.12.018 |