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Repurposing approved drugs as potential inhibitors of 3CL-protease of SARS-CoV-2: Virtual screening and structure based drug design
3CL proteases (3CL(pro)) are only found in RNA viruses and have a central role in polyprotein processing during replication. Therefore, 3CL(pro) has emerged as promising drug target for therapeutic treatment of infections caused by Coronaviruses. In the light of the recent major outbreak of the SARS...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Ltd.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832737/ https://www.ncbi.nlm.nih.gov/pubmed/32769050 http://dx.doi.org/10.1016/j.compbiolchem.2020.107351 |