Discovery of new acetylcholinesterase inhibitors for Alzheimer’s disease: virtual screening and in vitro characterisation

For more than two decades, the development of potent acetylcholinesterase (AChE) inhibitors has been an ongoing task to treat dementia associated with Alzheimer’s disease and improve the pharmacokinetic properties of existing drugs. In the present study, we used three docking-based virtual screening...

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Detalles Bibliográficos
Autores principales: David, Benoit, Schneider, Pascal, Schäfer, Philipp, Pietruszka, Jörg, Gohlke, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833026/
https://www.ncbi.nlm.nih.gov/pubmed/33478277
http://dx.doi.org/10.1080/14756366.2021.1876685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833026/
https://www.ncbi.nlm.nih.gov/pubmed/33478277
http://dx.doi.org/10.1080/14756366.2021.1876685

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