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Gα(i1) inhibition mechanism of ATP-bound adenylyl cyclase type 5

Conversion of adenosine triphosphate (ATP) to the second messenger cyclic adenosine monophosphate (cAMP) is an essential reaction mechanism that takes place in eukaryotes, triggering a variety of signal transduction pathways. ATP conversion is catalyzed by the enzyme adenylyl cyclase (AC), which can...

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Detalles Bibliográficos
Autores principales: Narzi, Daniele, van Keulen, Siri C., Röthlisberger, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833170/
https://www.ncbi.nlm.nih.gov/pubmed/33493164
http://dx.doi.org/10.1371/journal.pone.0245197