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Plasmodium falciparum erythrocyte membrane protein 1 variants induce cell swelling and disrupt the blood–brain barrier in cerebral malaria

Cerebral malaria (CM) is caused by the binding of Plasmodium falciparum–infected erythrocytes (IEs) to the brain microvasculature, leading to inflammation, vessel occlusion, and cerebral swelling. We have previously linked dual intercellular adhesion molecule-1 (ICAM-1)– and endothelial protein C re...

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Detalles Bibliográficos
Autores principales: Adams, Yvonne, Olsen, Rebecca W., Bengtsson, Anja, Dalgaard, Nanna, Zdioruk, Mykola, Satpathi, Sanghamitra, Behera, Prativa K., Sahu, Praveen K., Lawler, Sean E., Qvortrup, Klaus, Wassmer, Samuel C., Jensen, Anja T.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833209/
https://www.ncbi.nlm.nih.gov/pubmed/33492344
http://dx.doi.org/10.1084/jem.20201266