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Plasmodium falciparum erythrocyte membrane protein 1 variants induce cell swelling and disrupt the blood–brain barrier in cerebral malaria
Cerebral malaria (CM) is caused by the binding of Plasmodium falciparum–infected erythrocytes (IEs) to the brain microvasculature, leading to inflammation, vessel occlusion, and cerebral swelling. We have previously linked dual intercellular adhesion molecule-1 (ICAM-1)– and endothelial protein C re...
Autores principales: | Adams, Yvonne, Olsen, Rebecca W., Bengtsson, Anja, Dalgaard, Nanna, Zdioruk, Mykola, Satpathi, Sanghamitra, Behera, Prativa K., Sahu, Praveen K., Lawler, Sean E., Qvortrup, Klaus, Wassmer, Samuel C., Jensen, Anja T.R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833209/ https://www.ncbi.nlm.nih.gov/pubmed/33492344 http://dx.doi.org/10.1084/jem.20201266 |
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