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A Calcium Guard in the Outer Membrane: Is VDAC a Regulated Gatekeeper of Mitochondrial Calcium Uptake?

Already in the early 1960s, researchers noted the potential of mitochondria to take up large amounts of Ca(2+). However, the physiological role and the molecular identity of the mitochondrial Ca(2+) uptake mechanisms remained elusive for a long time. The identification of the individual components o...

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Detalles Bibliográficos
Autores principales: Sander, Paulina, Gudermann, Thomas, Schredelseker, Johann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833399/
https://www.ncbi.nlm.nih.gov/pubmed/33477936
http://dx.doi.org/10.3390/ijms22020946