High affinity binding of SARS-CoV-2 spike protein enhances ACE2 carboxypeptidase activity

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The novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) has emerged to a pandemic and caused global public health crisis. Human angiotensin-converting enzyme 2(ACE2) was identified as the entry receptor for SARS-CoV-2. As a carboxypeptidase, ACE2 cleaves many biological substrates besid...

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Detalles Bibliográficos
Autores principales: Lu, Jinghua, Sun, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Enzymology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833600/
https://www.ncbi.nlm.nih.gov/pubmed/33122196
http://dx.doi.org/10.1074/jbc.RA120.015303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833600/
https://www.ncbi.nlm.nih.gov/pubmed/33122196
http://dx.doi.org/10.1074/jbc.RA120.015303

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