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Ab-Ligity: identifying sequence-dissimilar antibodies that bind to the same epitope

Solving the structure of an antibody-antigen complex gives atomic level information of the interactions between an antibody and its antigen, but such structures are expensive and hard to obtain. Alternative experimental sources include epitope mapping and binning experiments, which can be used as a...

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Detalles Bibliográficos
Autores principales: Wong, Wing Ki, Robinson, Sarah A., Bujotzek, Alexander, Georges, Guy, Lewis, Alan P., Shi, Jiye, Snowden, James, Taddese, Bruck, Deane, Charlotte M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833755/
https://www.ncbi.nlm.nih.gov/pubmed/33448242
http://dx.doi.org/10.1080/19420862.2021.1873478