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Peripheral T cell receptor repertoire features predict durable responses to anti-PD-1 inhibitor monotherapy in advanced renal cell carcinoma

Immune checkpoint inhibitors (ICIs) offer significant clinical benefits to a subset of cancer patients via the induction of a systemic T cell-mediated anti-cancer immune response. Thus, the dynamic characterization of T cell repertoires in the peripheral blood has the potential to demonstrate noninv...

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Detalles Bibliográficos
Autores principales: Kato, Taigo, Kiyotani, Kazuma, Tomiyama, Eisuke, Koh, Yoko, Matsushita, Makoto, Hayashi, Yujiro, Nakano, Kosuke, Ishizuya, Yu, Wang, Cong, Hatano, Koji, Kawashima, Atsunari, Ujike, Takeshi, Fujita, Kazutoshi, Nonomura, Norio, Uemura, Motohide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833759/
https://www.ncbi.nlm.nih.gov/pubmed/33537170
http://dx.doi.org/10.1080/2162402X.2020.1862948