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Peripheral T cell receptor repertoire features predict durable responses to anti-PD-1 inhibitor monotherapy in advanced renal cell carcinoma
Immune checkpoint inhibitors (ICIs) offer significant clinical benefits to a subset of cancer patients via the induction of a systemic T cell-mediated anti-cancer immune response. Thus, the dynamic characterization of T cell repertoires in the peripheral blood has the potential to demonstrate noninv...
Autores principales: | Kato, Taigo, Kiyotani, Kazuma, Tomiyama, Eisuke, Koh, Yoko, Matsushita, Makoto, Hayashi, Yujiro, Nakano, Kosuke, Ishizuya, Yu, Wang, Cong, Hatano, Koji, Kawashima, Atsunari, Ujike, Takeshi, Fujita, Kazutoshi, Nonomura, Norio, Uemura, Motohide |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833759/ https://www.ncbi.nlm.nih.gov/pubmed/33537170 http://dx.doi.org/10.1080/2162402X.2020.1862948 |
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