Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy

Genetic mutations lead to the production of mutated proteins from which peptides are presented to T cells as cancer neoantigens. Evidence suggests that T cells that target neoantigens are the main mediators of effective cancer immunotherapies. Although algorithms have been used to predict neoantigen...

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Detalles Bibliográficos
Autores principales: Bai, Peng, Li, Yongzheng, Zhou, Qiuping, Xia, Jiaqi, Wei, Peng-Cheng, Deng, Hexiang, Wu, Min, Chan, Sanny K., Kappler, John W., Zhou, Yu, Tran, Eric, Marrack, Philippa, Yin, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833777/
https://www.ncbi.nlm.nih.gov/pubmed/33537173
http://dx.doi.org/10.1080/2162402X.2020.1868130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833777/
https://www.ncbi.nlm.nih.gov/pubmed/33537173
http://dx.doi.org/10.1080/2162402X.2020.1868130

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