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Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy
Genetic mutations lead to the production of mutated proteins from which peptides are presented to T cells as cancer neoantigens. Evidence suggests that T cells that target neoantigens are the main mediators of effective cancer immunotherapies. Although algorithms have been used to predict neoantigen...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833777/ https://www.ncbi.nlm.nih.gov/pubmed/33537173 http://dx.doi.org/10.1080/2162402X.2020.1868130 |