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Cholesterol 25-hydroxylase suppresses porcine deltacoronavirus infection by inhibiting viral entry

Cholesterol 25-hydroxylase (CH25 H) is a key enzyme regulating cholesterol metabolism and also acts as a broad antiviral host restriction factor. Porcine deltacoronavirus (PDCoV) is an emerging swine enteropathogenic coronavirus that can cause vomiting, diarrhea, dehydration and even death in newbor...

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Detalles Bibliográficos
Autores principales: Ke, Wenting, Wu, Xiaoli, Fang, Puxian, Zhou, Yanrong, Fang, Liurong, Xiao, Shaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833861/
https://www.ncbi.nlm.nih.gov/pubmed/33476696
http://dx.doi.org/10.1016/j.virusres.2021.198306