Ctcf haploinsufficiency mediates intron retention in a tissue-specific manner

CTCF is a master regulator of gene transcription and chromatin organisation with occupancy at thousands of DNA target sites genome-wide. While CTCF is essential for cell survival, CTCF haploinsufficiency is associated with tumour development and hypermethylation. Increasing evidence demonstrates CTC...

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Detalles Bibliográficos
Autores principales: Alharbi, Adel B, Schmitz, Ulf, Marshall, Amy D, Vanichkina, Darya, Nagarajah, Rajini, Vellozzi, Melissa, Wong, Justin JL, Bailey, Charles G, Rasko, John EJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834090/
https://www.ncbi.nlm.nih.gov/pubmed/32816606
http://dx.doi.org/10.1080/15476286.2020.1796052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834090/
https://www.ncbi.nlm.nih.gov/pubmed/32816606
http://dx.doi.org/10.1080/15476286.2020.1796052

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